Breztri: A Guide for Managing COPD

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease that makes it difficult to breathe.


Understanding Breztri: A Comprehensive Guide for Managing COPD

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease that makes it difficult to breathe. It encompasses conditions like emphysema and chronic bronchitis, leading to symptoms such as shortness of breath, coughing, and wheezing. Managing COPD effectively often involves a combination of treatments, and for some individuals, a prescription medication called Breztri may be part of their care plan.

What is Breztri?

Breztri (budesonide, glycopyrrolate, and formoterol fumarate) is a prescription inhaled medication used for the maintenance treatment of COPD. It is designed to help improve lung function and reduce the frequency of COPD exacerbations (flare-ups) over time. It is not intended for the relief of sudden breathing problems and should not be used as a rescue inhaler.

This medication is a "triple therapy" inhaler, meaning it contains three different active ingredients:


  • Budesonide: An inhaled corticosteroid (ICS) that helps to reduce inflammation in the airways.

  • Glycopyrrolate: A long-acting muscarinic antagonist (LAMA) that helps to relax the muscles around the airways, making them wider and easier to breathe through.

  • Formoterol Fumarate: A long-acting beta2-agonist (LABA) that also helps to relax the muscles in the airways, providing bronchodilation.

How Breztri Works

The three active ingredients in Breztri work together to address different aspects of COPD. Budesonide targets the inflammatory processes within the lungs, which are common in COPD. Glycopyrrolate and formoterol fumarate act as bronchodilators, meaning they help to open up the airways. By reducing inflammation and widening the airways, Breztri aims to make breathing easier and decrease the likelihood of COPD exacerbations.

The combination of these three types of medications in a single inhaler provides a convenient and comprehensive approach to managing the persistent symptoms of COPD, helping patients maintain better lung function day-to-day.

Who is Breztri For?

Breztri is specifically approved for the long-term, once-daily maintenance treatment of COPD in adults. It is typically prescribed to individuals who require treatment with a combination of an inhaled corticosteroid and a long-acting bronchodilator. It is important to note that Breztri is not used to treat asthma or acute bronchospasm, and it should not be given to children.

Important Considerations When Using Breztri

Like all prescription medications, using Breztri comes with important considerations. Patients should always follow their healthcare professional's instructions carefully.

Usage and Dosage

Breztri is typically administered as a specific number of inhalations, usually once daily. It is crucial to use the inhaler correctly as instructed by your doctor or pharmacist, as proper technique ensures the medication reaches the lungs effectively. Do not use more than the prescribed dose or use it more often than prescribed.

Potential Side Effects

While generally well-tolerated, Breztri can cause side effects. These can vary from person to person and may include common issues like oral thrush (a fungal infection in the mouth and throat), hoarseness, headache, or flu-like symptoms. More serious side effects are possible. It is essential to discuss any concerns or adverse reactions with your healthcare provider. A comprehensive list of potential side effects and warnings can be found in the medication's official prescribing information.

Consulting Your Healthcare Professional

Before starting any new medication, including Breztri, it is vital to have a thorough discussion with your doctor. They will assess your overall health, current medications, and medical history to determine if Breztri is the right treatment option for you. Always inform your doctor about all medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential interactions. Never stop using Breztri or change your dosage without consulting your healthcare provider first.

Living with COPD and Breztri

Managing COPD is an ongoing process that often involves a combination of medication, lifestyle adjustments, and regular medical follow-ups. When prescribed, Breztri can be an important part of a comprehensive treatment plan to help improve breathing and reduce flare-ups. Adhering to your prescribed treatment, maintaining a healthy lifestyle, and communicating openly with your healthcare team are key to living well with COPD.